Correction to “Calcium-Mediated Control of S100 Proteins: Allosteric Communication via an Agitator/Signal Blocking Mechanism”
نویسندگان
چکیده
منابع مشابه
Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins.
Ndr is a nuclear serine/threonine protein kinase that belongs to a subfamily of kinases identified as being critical for the regulation of cell division and cell morphology. The regulatory mechanisms that control Ndr activity have not been characterized previously. In this paper, we present evidence that Ndr is regulated by EF-hand calcium-binding proteins of the S100 family, in response to cha...
متن کاملS100 Calcium Binding Proteins and Ion Channels
S100 Ca(2+)-binding proteins have been associated with a multitude of intracellular Ca(2+)-dependent functions including regulation of the cell cycle, cell differentiation, cell motility and apoptosis, modulation of membrane-cytoskeletal interactions, transduction of intracellular Ca(2+) signals, and in mediating learning and memory. S100 proteins are fine tuned to read the intracellular free C...
متن کاملThe Mechanism of the Effect of Calcium-blocking Drugs on the Treatment of Angina
Dans cet article Jes auteurs ont rappele les bases physiopathologiques et mecanisme d'action des antagonistes de (Ca + ) dans le traitement de l'angine de poitrine.
متن کاملEvolution of the S100 family of calcium sensor proteins.
The S100s are a large group of Ca(2+) sensors found exclusively in vertebrates. Transcriptomic and genomic data from the major radiations of mammals were used to derive the evolution of the mammalian S100s genes. In human and mouse, S100s and S100 fused-type proteins are in a separate clade from other Ca(2+) sensor proteins, indicating that an ancient bifurcation between these two gene lineages...
متن کاملSHORT COMMUNICATION A Portable Allosteric Mechanism
Theallostericmechanismbywhich the gene expression regulatory protein AraC regulates its DNA-binding activity is shown to be portable by grafting it to -galactosidase, generating an arabinose-regulated -galactosidase. A portion of the -peptide sequence that complements the activity of -acceptor -galactosidase was inserted into a nonessential region of the regulatory peptidyl arm of AraC protein....
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2018
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.8b06612